Atlas Supports a New World of Neurogenomics

摘要

One of the delights of scanning the most highly cited papers is the opportunity to be at least vaguely aware of a huge range of subjects. One of the drawbacks is that it is impossible to be more than vaguely aware. Sometimes a paper is so astonishing that it is difficult not to be struck dumb. Such a paper is at #10.rn"Genome-wide atlas of gene expression in the adult mouse brain" beggars belief. It maps, in three dimensions, which of more than 20,000 genes is expressed where in the mouse brain. Not a vague hand-waving where, like "the neo-cortex," but a precise location that might be no more than a few cells in volume.