Harnessing GWAS for Insights, in Alzheimer's and in General

摘要

Genome-wide association studies (GWAS) are the hot new tool for getting to grips with genes and diseases. Look at enough people, in enough detail, and researchers can detect genetic associations with weak effects that may nevertheless point the way to a deeper understanding. Latest to succumb to this kind of scrutiny and enter the Top Ten is Alzheimer's disease, with papers at #7 and #8. Coinciden-tally-or not-just ahead of them at #6 is a valuable overview of the GWAS phenomenon.