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Decisional Capacity of Patients With Schizophrenia to Consent to Research: Taking Stock

机译:精神分裂症患者同意研究的决策能力:盘点

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摘要

With the growth in recent years of studies of decisional capacity for research among people with schizophrenia, this is an opportune time to ask three questions: What have we learned from these studies? What remains to be learned? And what normative issues still need to be resolved? Among the things learned are that patients with schizophrenia, as a group, have lower scores on measures of decisional capacity than normals, but higher performance than patients with dementia. However, performance is highly variable within the group, correlates most strongly with neuropsychological impairment, and seems susceptible in many patients to successful remediation. The issues that remain in need of exploration include the development of a brief screening instrument for decisional capacity that can be used routinely, and the identification of those patients most likely to benefit from more intensive informational procedures. Finally, among the normative issues still in need of resolution are the degree of capacity needed to consent to research participation, how to deal with fluctuating capacity during research projects, and the legitimate extent of surrogate consent for participation of incompetent patients in research.
机译:随着近年来精神分裂症患者决策能力研究的增长,现在是时候提出三个问题了:我们从这些研究中学到了什么?还有什么要学习?哪些规范性问题仍需要解决?所获知识当中,精神分裂症患者作为一个整体,其决策能力指标得分低于正常人,但其表现却高于痴呆症患者。但是,该组中的表现变化很大,与神经心理障碍最密切相关,并且似乎在许多患者中容易成功治愈。仍需探索的问题包括开发一种可常规使用的简短决策能力筛查工具,并确定最有可能从更密集的信息程序中受益的患者。最后,在尚需解决的规范性问题中,包括同意研究参与所需的能力程度,如何处理研究项目过程中的波动能力,以及对不称职的患者参与研究的替代同意的合理程度。

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  • 来源
    《Schizophrenia Bulletin》 |2006年第1期|22-25|共4页
  • 作者

    Paul S Appelbaum;

  • 作者单位

    Department of Psychiatry University of Massachusetts Medical School Worcester MA 01655;

    as of January 1 2006 Department of Psychiatry College of Physicians and Surgeons Columbia University;

    as of January 1 2006 Division of Psychiatry Law and Ethics New York State Psychiatric Institute 1051 Riverside Drive New York NY 10032;

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  • 入库时间 2022-08-18 01:07:36

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