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ALTERNATIVE METHODS FOR STATISTICAL CHARACTERIZATION AND QUANTIFICATION OF CRYPTOSPORIDIUM SPP. GP60 GENE VARIABILITY

机译:隐孢子虫SPP的统计表征和定量分析的替代方法。 GP60基因变异

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摘要

In this paper we used statistical methods for to study DNA sequences different species of Cryptosporidium: two reference DNA sequences from public GenBank database and one sample DNA sequence isolated and analyzed by sequencing in our laboratory, which was proposed to be deposited in GenBank. Using statistical concepts as Shannon entropy, Onicescu informational energy, different statistical distances types we ordered the three DNA sequences according to their structure variability. We have also introduced two indices: the index associated to structural information quantities Shannon entropy and Onicescu energy and the altered index associated to the structural discrepancy quantity, respectively. We have approach firstly these statistical methods for Cryptosporidium.
机译:在本文中,我们使用统计学方法研究了不同种类的隐孢子虫的DNA序列:从公共GenBank数据库中获得了两个参考DNA序列,并在我们的实验室中通过测序分离并分析了一个样本DNA序列,建议将其存放在GenBank中。使用统计概念,如Shannon熵,Onicescu信息能量,不同的统计距离类型,我们根据三个DNA序列的结构变异性对其进行排序。我们还引入了两个指数:分别与结构信息量Shannon熵和Onicescu能量相关的指数以及与结构差异量相关的变化指数。我们首先采用隐孢子虫的这些统计方法。

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  • 来源
    《Romanian reports in physics》 |2014年第3期|683-692|共10页
  • 作者单位

    'Carol Davila' University of Medicine and Pharmacy, Department of Parasitology, D.Gerota19-21, Bucharest, Romania,National Institute of Research and Development for Microbiology and Immunology 'Cantacuzino', Splaiul Independentei 103, Bucharest, Romania;

    Institute of Mathematical Statistics and Applied Mathematics of Romanian Academy, Department of Mathematical Modelling in Life Sciences, 13, Calea 13 Septembrie, Bucharest, Romania,University of Bucharest, Department of Physiology and Biophysics, Faculty of Biology, Spl. Independentei 91-95, Bucharest, Romania;

    National Institute for Nuclear Physics and Engineering, P.O.Box MG-6, RO-077125, Bucharest-Magurele, Romania;

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  • 原文格式 PDF
  • 正文语种 eng
  • 中图分类
  • 关键词

    DNA sequences; Cryptosporidium variability; gp60 gene; statistical methods;

    机译:DNA序列;隐孢子虫变异性;gp60基因;统计方法;

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