IMPROVED PERFORMANCE IN GAP-FILLING FOR LC-MS PEAK DETECTION

摘要

This work describes a method of detecting a missing peak, avoiding the cosily process of re-opening a rawfile to re-detect a missed peak. It does so by findinga 'peak' in every rawfile when one is found in any rawfile. Thus, all rawfiles are pcak-detected together, so missing peaks are corrected immediately. If there is simply noise at the peak location for one or more rawfiles, the method will return the height of the baseline-corrected noise and an indication that no peak could be detected.