NOVEL BLEND OF BOTANICAL EXTRACTS WITH PROVEN COSMETIC SLIMMING ACTIVITY

摘要

The present invention is related to the field of molecular biology, more precisely to molecular biology applied to cosmetics, even more precisely to a novel blend of botanical extracts. Arcfostaphylos uva-ursi Leaf Extract and Silybum marianum Extract and compositions containing said botanical extracts, showing a novel slimming efficacy via reducing fat volume and/or eliminating signs of lipid accumulation (cellulite). The invention comprises also the novel mechanism of action by which exerts this activity, that is, the increase in the release of NRG4 by adipose cells through which a decrease in lipidic content is achieved, by both acting on lipolysis and adipogenesis. Additionally, the botanical blend has proved to be able to reduce the uptake of glucose. Moreover, the novel blend is able to act as an inductor of sympathetic innervation of adipose tissue, needed to activate thermogenic functions.