Some Theoretical Considerations on Calorimetrically Determined Bactericidality of Antimicrobial Drugs and Its Concentration Dependence

摘要

Based on the theory to characterize the bacteriostatic and bactericidal actions of drugs proposed by Takahashi, further theoretical considerations were attempted on the bactericidality of a drug and its concentration dependence. An index term to show the bactericidality as a function of drug concentration was defined and the concentration dependence was graphically drawn on the basis of inhibitory parameters determined calorimetrically.