Synthetic routes to responsive polymers; co-polycondensation of tri-functioanl amion acids with diacylchlorides

摘要

The condensation of diamino acids and their drivatives such as L-lysine ethyl ester and L-ornithine with aromatic and aliphatic diacyl chlorides was investigated. Linear polyamides bearing carboxylic acid or ester functional groups pendant to the backbone with reasonable molecular weight (M_W 56-66 kDa) could be produced using either a sinlge phase aqueous acetone solution method or a bi-phasic carbon tetrachloride/aqueous method. The effect of reaction conditions on product yield and molecular weight were also investigated.