Inappropriate utilization of intravenous proton pump inhibitors in hospital practice—a prospective study of the extent ofn the problem and predictive factors

摘要

Background: Intravenous (IV) proton pump inhibitors (PPI) reduce rebleeding from high-risk peptic ulcers following endoscopic therapy. The majority of IV PPI prescriptions in US hospital practice are inappropriate, leading to unnecessary drug costs, drug shortages and potential adverse events. To date, little is known about UK hospital IV PPI prescribing practice.