Photosensitized splitting of cis-syn 1,3-dimethyluracil dimer by tryptophan and its peptides

摘要

Photosensitized splitting of cis-syn 1,3-dimethyluracil dimer by tryptophan (Trp) and its peptides (Trp-Tyr and Trp-Phe) is studied by fluorescence quenching experiments and irradiation experiments. It reveals that 1,3-dimethyluracil dimer is mainly s plit by e_(aq)~- resulting from two-photon ionization of Trp and its peptides under irradiation with light (A >290 nm). Moreover, the excited singlet state of Trp and its peptides can transfer an electron to the dimer, "which splits and gives two pyrimid ines. In addition, because of its lower oxidative potential, the excited triplet state of Trp-Tyr can also split the dimer via transfering an electron to the dimer.