Evaluation of sterlizing efficacy of,ultrasonic fogging with hypochlorite or slightly acid electrolzed solutions in an actual large space Recently attention has been focused on countermeasures against microorganisms such as viruses and microbe, in connection with pandemics of new forms of influenza or SARS, and the occurrence of bioterrorism. Also, in pharmaceutical or food production facilities, a high standard of internal environment of the facility is required, including countermeasures against microorganisms. These countermeasures from the facility point of view include partitioning of work zones (zoning), and cleaning the air using HEPA filters. However, when workers/researchers are working within a facility, dispersion of dust or adhering microbe brought in from clothes, etc., cause pollution of the air. In this report, the sterilization performance of weak acid hypochlorous solution used as the chemical substance was verified. In addition, the sterilization performance in an actual space varied not only with the chemical substance used, but also with the condition of the room, the air conditioning system, the method of spraying, etc. Therefore, from the above sterilization performance tests using chemical substances, the raw data required for a computational fluid mechanics (CFD) model were derived. A method that enables the effect of the chemical substance to be predicted under various conditions was investigated, and the results are reported.%最近，新型インフルモンザやSARSなどのパンデミックの発生ゃバィオテロに関し,ウィルスや真菌•細菌などの微生物対策が注目されている。また，医薬品や食品の生産施設では，微生物対策を含めた高い水準の設施内環境が求められている。施設面からの微生物対策として，作業区分の区画(ゾーニング)化やHEPAフィルターを用いた空気の清浄化などが一般的である。しかし，施設內で作業員が作業する場合は，衣類や持込まれる機器などからの塵埃や付着菌の飛散が空気汚染の原因となる場合がある。そのため，施設面のみの対策だけでは，微生物の制御は不充分であり，何らかの直接的な殺菌技術が必要となる。
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