Synthesis and characterization of copper (Ⅱ) complexes of adenine and aminoacids

摘要

Complexes [Cu(CH_3COO)(ade-H)(H_2O)] H_2O) (Ⅰ), [Cu(CH_3COO) (ade-H)(0.5 ade) (0.5 H_2O)] 2H_2O (Ⅰa), [Cu(CH_3COO)(ade-H)(ade)] 2H_2O] (Ⅰb), [Cu(ClCH_2COO)(ade-H) (H_2O)] H_2O (Ⅱ), [(Cu(CNCH_2COO)(ade-H)(H_2O)] H_2O (Ⅲ), where ade = adenine (C_5H_5N_5), have been prepared. Ⅰ, Ⅱ and Ⅲ on interaction with aminoacids such as glycine, alanine or glutamic acid give the complexes of the type [Cu(XCH_2COO)(aa)(ade)(2H_2O)], where X=H, Cl or CN and Haa = aminoacid, which are characterized by elemental and thermal analyses, electronic, infrared and EPR spectroscopic studies and variable temperature magnetic susceptibility measurements. Simple adeninato complexes are found to be dimeric, involving the bridging of the anionic adenine through the imidazole (N9) and the pyrimidine (N3) nitrogens and the acetato group through the carboxylate oxygens, while mixed adenine-aminoacidato complexes are monomeric, involving the bonding of the N(7) of adenine, the oxygen of acetate and chelation of the aminoacid, in addition to the coordination of water molecules.