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Synthesis and X-ray diffraction data of 7-methyl-cis-2-(1'-naphthyI)- 2,3,4,5-tetrahydro-1H-benzo[b]azepin-4-ol

机译:7-甲基-顺-2-(1'-萘I)-2,3,4,5-四氢-1H-苯并[b]氮杂-4-醇的合成及X射线衍射数据

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摘要

The 7-methyl-cis-2-(r-naphthyl)-2,3,4,5-tetrahydro-1H-benzo[b]azepin-4-ol (chemical formula C_(21)H_(21)NO) was prepared via the reductive cleavage of the bridged N-O bond of the corresponding 7-methyl-2-exo-(l'-naphthyl)-l,4-epoxytetrahydro-l-benzazepine. The X-ray powder diffraction pattern for the new compound was analyzed and found that the title compound crystallizes in a monoclinic system with space group P2/c (No. 13) and refined unit-cell parameters a- 11.012(2), b= 18.613(5), c = 7.316(4) A, β= 102.88(3) ° and V= 1461.8(7) A~3.
机译:7-甲基-顺-2-(r-萘基)-2,3,4,5-四氢-1H-苯并[b]氮杂-4-醇(化学式C_(21)H_(21)NO)为通过还原性裂解相应的7-甲基-2-exo-(l'-萘基)-1,4-环氧四氢-1-苯并ze庚因的桥连NO键制备。分析了该新化合物的X射线粉末衍射图,发现标题化合物在具有P2 / c空间组(第13号)和精确的晶胞参数a-11.012(2)的单斜晶系统中结晶,b = 18.613(5),c = 7.316(4)A,β= 102.88(3)°,V = 1461.8(7)A〜3。

著录项

  • 来源
    《Powder diffraction》 |2011年第s1期|p.S55-S57|共3页
  • 作者单位

    Grupo de Investigation en Quimica Estructural (GIQUE), Escuela de Quimica, Facultad de Ciencias, Universidad Industrial de Santander, A.A. 678, Carrera 27, Calle 9 Ciudadela Universitaria. Bucaramanga, Colombia;

    Grupo de Investigation en Quimica Estructural (GIQUE), Escuela de Quimica, Facultad de Ciencias, Universidad Industrial de Santander, A.A. 678, Carrera 27, Calle 9 Ciudadela Universitaria. Bucaramanga, Colombia;

    Laboratorio de Sintesis Orgdnica (LSO), Facultad de Ciencias, Universidad Industrial de Santander, A.A. 678, Carrera 27, Calle 9 Ciudadela Universitaria. Bucaramanga, Colombia;

    Laboratorio de Sintesis Orgdnica (LSO), Facultad de Ciencias, Universidad Industrial de Santander, A.A. 678, Carrera 27, Calle 9 Ciudadela Universitaria. Bucaramanga, Colombia;

  • 收录信息 美国《科学引文索引》(SCI);美国《生物学医学文摘》(MEDLINE);
  • 原文格式 PDF
  • 正文语种 eng
  • 中图分类
  • 关键词

    tetrahydro-1-benzazepine; X-ray powder diffraction data; antiparasitic agents;

    机译:四氢-1-苯并ze庚因;X射线粉末衍射数据;抗寄生虫药;

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