TOXIC EFFECT OF THREE PESTICIDES (FENVALERATE, ISOPROTURON AND ZIRAM) AND THEIR MIXTURE ON ALBINO RATS

摘要

The pesticides name Fenvalerate, Isoproturon & Ziram given orally with ground nut oil to Albino Rats. These pesticides was administered as acute (1,2 days) and chronic (15,30 60 days) exposure singly and in mixture of three pesticides, control run simultaneously. The study revealed significant elevation in serum GOT and GPT, while cause decrease in case of Cholinesterase activities. In case of alkaline and acid phosphatases significant increase has been recorded. From the biochemical data a joint action was estimated for mixture of Fenvalerate, Isoproturon and Ziram. The mixture interact additive with SGOT, SGPT and Acid phosphatase while antagonistically with AChE and Alkaline phosphatase enzymes.