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Performance Evaluation of Compton Micro-PET for Detector Modalities: A Monte Carlo Study

机译:用于检测器形式的康普顿微型PET性能评估:蒙特卡洛研究

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摘要

Performance of Compton positron emission tomography (PET) is studied in this paper using qualitative and quantitative methods. Lutetium yttrium oxyorthosilicate (LYSO), lutetium-gadolinium oxyorthosilicate (LGSO), and CdZnTe (CZT) materials are used for Compton PET. LYSO is widely used for conventional PET, and LGSO is a prospective scintillator material for PET detectors. CZT is one of the semiconductor materials that have high energy and position resolution. For conventional PET, only the photoelectric effect is considered a valid interaction for image reconstruction. However, Compton scattering tracing technology is applied for our Compton PET to additionally use Compton scattering events for image reconstruction. It is relatively difficult to use multiple layers for PET made of scintillators, as electronic circuits must be attached to each layer. For this reason, conventional PET generally uses only one layer for each detector module and limits the spatial resolution in the depth direction. In contrast, it is possible for a CZT detector to measure a depth of interest based on the cathode-to-anode signal ratio or electron drift time with relatively simple electronic circuits. Furthermore, CZT materials have high spatial and energy resolutions. Therefore, the position and energy information of the radiation interactions in the detector module can be precisely calculated to determine the interaction sequence, and hence, the information from the Compton scattering can be used for image reconstruction in PET. For this reason, the reconstructed image of CZT PET can show better quality than those of scintillator PETs. The detection efficiency and quality of the reconstructed image are significantly increased by including the Compton scattering effect as a valid interaction process for image reconstruction because Compton scattering has twice the interaction probability of the photoelectric effect at 511 keV. In this paper, the effectiveness of including Compton scattering events for PET reconstruction was evaluated for scintillators and CZT semiconductor detectors. The maximum likelihood expectation and maximisation reconstruction method was applied for conventional and Compton PET reconstruction, and the qualities of the reconstructed images were evaluated.
机译:本文采用定性和定量方法研究了康普顿正电子发射断层显像(PET)的性能。康普顿PET使用氧化原酸钇(LYSO),氧化silicate原-(LGSO)和CdZnTe(CZT)材料。 LYSO被广泛用于常规PET,LGSO是用于PET检测器的预期闪烁体材料。 CZT是具有高能量和位置分辨率的半导体材料之一。对于常规PET,仅光电效应被认为是图像重建的有效相互作用。但是,我们的康普顿PET应用了康普顿散射跟踪技术,以另外使用康普顿散射事件进行图像重建。对于由闪烁体制成的PET,要使用多层结构是相对困难的,因为必须将电子电路连接到每一层上。由于这个原因,常规PET通常对于每个检测器模块仅使用一层并且限制深度方向上的空间分辨率。相比之下,CZT检测器可以使用相对简单的电子电路基于阴极与阳极的信号比或电子漂移时间来测量目标深度。此外,CZT材料具有很高的空间和能量分辨率。因此,可以精确地计算探测器模块中辐射相互作用的位置和能量信息,以确定相互作用序列,因此,来自康普顿散射的信息可以用于PET中的图像重建。因此,与闪烁体PET相比,CZT PET的重建图像可以显示出更好的质量。通过将康普顿散射效应作为图像重建的有效交互过程,可以显着提高重建图像的检测效率和质量,因为康普顿散射的光电二极管在511 keV处的相互作用概率是后者的两倍。在本文中,对闪烁器和CZT半导体探测器评估了包含Compton散射事件以进行PET重建的有效性。将最大似然期望和最大化重建方法应用于常规重建和Compton PET重建,并评估了重建图像的质量。

著录项

  • 来源
    《Nuclear Technology》 |2018年第3期|386-395|共10页
  • 作者

    Yoon Changyeon; Lee Wonho;

  • 作者单位
  • 收录信息 美国《科学引文索引》(SCI);美国《工程索引》(EI);美国《生物学医学文摘》(MEDLINE);
  • 原文格式 PDF
  • 正文语种 eng
  • 中图分类
  • 关键词

  • 入库时间 2022-08-18 04:06:30

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