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Initial experimental studies of using solid-state photomultiplier for PET applications

机译:在PET应用中使用固态光电倍增管的初步实验研究

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An evaluation of solid-state photomultiplier (SSPM) has been conducted for Positron Emission Tomography (PET) applications. The single-channel PET detector has been measured for its performance with respect to linearity of light detection, energy resolution, coincidence timing resolution, and depth-of-interaction detection capability. The SSPMs used have a 1 × 1 mm~2 active detection area. At nominal bias, it has a peak sensitivity around 470 nm, typical single photon detection efficiency around 20%, gain about 600,000, dark current 25 μA, and excess noise factor < 1.3. A trans-impedance preamplifier was used to read the signal under operating conditions consisted with a balanced energy and timing performance for the PET application. In this initial study, there was a geometry mismatch between the SSPM and LSO crystal with a 2 × 2 mm~2 cross-sectional area, where the light loss could reach 75%. Measured energy and coincidence timing resolutions are 23% and 1.8 ns, respectively, all within the SSPM linear region of photon detection up to ~250 photoelectrons. The depth-of-interaction (DOI) resolution was measured with two SSPMs detecting lights at both ends of a 1.8 × 2 × 20 mm~3 LSO crystal, using a conventional electronic collimation method to localize the DOI positions. The measured DOI resolution was 4.5 ( + /-0.3) mm, sufficient to develop a PET detector for the measurement of 3D interaction locations. These preliminary measurements have demonstrated the feasibility of using SSPMs for PET applications.
机译:已对正电子发射断层扫描(PET)应用进行了固态光电倍增管(SSPM)评估。已对单通道PET检测器的光检测线性度,能量分辨率,同时定时分辨率和交互作用深度检测能力进行了测量。使用的SSPM具有1×1 mm〜2的有效检测区域。在标称偏置下,它的峰值灵敏度约为470 nm,典型的单光子检测效率约为20%,增益约为600,000,暗电流为25μA,且多余噪声因子<1.3。在PET应用中,在具有平衡能量和定时性能的工作条件下,使用跨阻前置放大器读取信号。在此初始研究中,SSPM与LSO晶体之间的几何失配具有2×2 mm〜2的横截面积,其中光损失可能达到75%。所测得的能量和重合时序分辨率分别为23%和1.8 ns,都在光子检测的SSPM线性范围内,最多约250个光电子。交互深度(DOI)分辨率是通过两个SSPM在1.8×2×20 mm〜3 LSO晶体的两端检测光来测量的,使用常规的电子准直方法确定DOI的位置。测得的DOI分辨率为4.5(+/- 0.3)毫米,足以开发出用于检测3D交互位置的PET检测器。这些初步测量证明了将SSPM用于PET应用的可行性。

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