首页> 外文期刊>Nuclear Instruments & Methods in Physics Research. Section A, Accelerators, Spectrometers, Detectors and Associated Equipment >1 kHz laser accelerated electron beam feasible for radiotherapy uses:A PIC-Monte Carlo based study
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1 kHz laser accelerated electron beam feasible for radiotherapy uses:A PIC-Monte Carlo based study

机译:1 kHz激光加速电子束可用于放射疗法:基于PIC-Monte Carlo的研究

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摘要

Laser wakefield acceleration (LWFA) offers a promising compact solution for the production of high and very high energy electron (VHEE) beams, which have an ultrashort pulse duration with a high instantaneous dose rate and small source size. These unique properties are of radiobiological as well as clinical interest. In this paper we focus on the potential application of high repetition rate LWFA electron beams for radiobiology and radiotherapy. On the basis of particle-in-cell (PIC) and Monte Carlo simulations we propose that, using a commercially available 1kHz laser system one can generate electron beams with 35.7 MeV mean energy and 3pC electron bunch charge at 1kHz repetition rate to deliver a dose rate of 18Gy/min, which could be extremely useful for real radiotherapy applications. Thanks to the high repetition rate, dose delivery can be performed with high precision making this system a potential alternative to conventional clinical electron accelerators.
机译:激光韦克菲尔德加速度(LWFA)为生产高能高能量电子(VHEE)梁提供了一个有前途的紧凑型解决方案,其具有高瞬时剂量率和小源极尺寸的超短脉冲持续时间。这些独特的性质是辐射生物学以及临床兴趣。在本文中,我们专注于高重复率LWFA电子束进行辐射生物学和放射疗法的潜在应用。基于粒子 - 细胞(PIC)和蒙特卡罗模拟,我们提出,使用市售的1KHz激光系统,可以在1KHz重复率下以35.7MeV的平均能量和3PC电子束充电产生电子束以递送剂量18冰/分钟的速率对于真正的放射疗法应用来说非常有用。由于高重复率,可以用高精度进行剂量递送,使得该系统成为常规临床电子促进剂的潜在替代方案。

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  • 作者单位

    ELI-ALPS ELI-HU Non-Profit Ltd. Wolfgang Sandner u. 3 H-6728 Szeged Hungary;

    ELI-ALPS ELI-HU Non-Profit Ltd. Wolfgang Sandner u. 3 H-6728 Szeged Hungary National Laboratory on High Power Laser and Physics SIOM CAS Shanghai 201800 China Department of Plasma and Nuclear Fusion Nuclear Research Center Atomic Energy Authority Abu-Zabal 13759 Egypt;

    ELI-ALPS ELI-HU Non-Profit Ltd. Wolfgang Sandner u. 3 H-6728 Szeged Hungary;

    ELI-ALPS ELI-HU Non-Profit Ltd. Wolfgang Sandner u. 3 H-6728 Szeged Hungary;

    ELI-ALPS ELI-HU Non-Profit Ltd. Wolfgang Sandner u. 3 H-6728 Szeged Hungary;

    ELI-ALPS ELI-HU Non-Profit Ltd. Wolfgang Sandner u. 3 H-6728 Szeged Hungary;

    ELI-ALPS ELI-HU Non-Profit Ltd. Wolfgang Sandner u. 3 H-6728 Szeged Hungary;

    ELI-ALPS ELI-HU Non-Profit Ltd. Wolfgang Sandner u. 3 H-6728 Szeged Hungary;

    ELI-ALPS ELI-HU Non-Profit Ltd. Wolfgang Sandner u. 3 H-6728 Szeged Hungary University of Szeged Faculty of Medicine Department of Oncotherapy Koranyi fasor 12. H-6720 Szeged Hungary;

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  • 正文语种 eng
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  • 关键词

    LWFA acceleration; Electron radiotherapy;

    机译:LWFA加速;电子放射疗法;

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