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Defence strategies

机译:防御策略

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摘要

IMMUNOLOGIST Charles Janeway had an audacious idea. It was 1989 and most of his colleagues thought the immune system was primed solely to detect molecules it hadn't seen before. Janeway thought he had evidence that novelty alone wasn't enough to mobilise the body's full defences. He proposed that a second signal was needed to tell if a foreign substance was a threat or not. That signal, he predicted, would come from cells pre-installed with receptors that lock onto specific molecules found on viruses, bacteria and the like.
机译:免疫学家Charles Janeway有一个大胆的想法。 1989年,他的大多数同事都认为免疫系统只是为了检测以前从未见过的分子而准备好的。珍妮威(Janeway)认为他有证据表明,仅凭新颖性还不足以动员人体的全部防御力。他建议需要第二个信号来判断异物是否构成威胁。他预测,该信号将来自预装有受体的细胞,这些受体锁定在病毒,细菌等上发现的特定分子上。

著录项

  • 来源
    《New scientist》 |2018年第3163期|46-46|共1页
  • 作者

    Jeremy Webb;

  • 作者单位
  • 收录信息 美国《科学引文索引》(SCI);美国《化学文摘》(CA);
  • 原文格式 PDF
  • 正文语种 eng
  • 中图分类
  • 关键词

  • 入库时间 2022-08-18 02:50:59

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