A model of the IT-PF network in object working memory which includes balanced persistent activity and tuned inhibition

摘要

The properties of cells in the prefrontal cortex and inferotemporal cortex recorded in monkeys performing delayed matching-to-sample tasks with intervening visual stimuli and memory guided attention tasks are reproduced by means of a model in which two networks of leaky integrate-and-fire neurons representing the two cortical areas interact reciprocally. Each of the networks is organized in micro-columns (M-Cs) which leads naturally to a dynamic balance between excitation and inhibition within each M-C so that realistic cortical spiking statistics (low firing rates with higher or equal to one CVs) are obtained.