Detecting and Estimating Signals in Noisy cable Structure, Ⅰ: Neuronal Noise Sources

摘要

In recent theoretical approaches addressing the problem of neural cod- ing, tools from statistical estimation and information theory have been applied to quantify the ability of neurons to transmit information through their spike outputs. These techniques, though fairly general, ignore the specific nature of neuronal processing in terms of its known biophysical properties. However, a systematic study of processing at various stages in a biophysically faithful model of a single neuron can identify the role of each stage in information transfer.