A structured weight management programme can achieve improved functional ability and significant weight loss in obese patients with chronic kidney disease

摘要

Background. Kidney transplantation in obese patients [body mass index (BMI) 30 kg/m2] is associated with a poorer outcome, and these patients are therefore often excluded from transplant waiting lists. Conventional weight loss strategies based on a high fibre, low energy diet and exercise are often unsuitable in the chronic kidney disease (CKD) population. A comprehensive multidisciplinary weight management programme comprising a low fat, reduced energy diet, individual exercise prescription and pharmacotherapy with orlistat 120 mg tds, was initiated to determine whether obese patients with CKD could reach an acceptable weight for transplantation.