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Growth industry

机译:成长产业

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Discoveries in cell and molecular biology, new tools such as gene-expression profiling, and information from the human genome sequence are converging to brighten employment prospects in industrial cancer research. Two of the first cancer drugs to use these sources for 'rational' design ― Herceptin, a protein-based treatment for breast cancer, and Gleevec, a small-molecule chemotherapeutic for some forms of leukaemia ― are proving successful, and others such as Avastin and Erbitux are already following in their footsteps. This trend has created some bright spots in cancer R&D recruitment, even though drug discovery in general has been adversely affected by mergers, a few high-profile failures and a shaky US economy. "Everyone is recognizing that there are going to be a lot of opportunities with all of the new information," says Jeff Hanke, vice-president for cancer research at AstraZeneca R&D Boston in Waltham, Massachusetts. Strong medical demand and a tremendous amount of new science makes this the time for a big push, he says. With that in mind, the company has taken on R&D staff in the United States and Britain during the past few years and built a new cancer facility in Waltham. And although opportunities are patchy, with some companies expanding cancer research and some not, there is currently a general upswing in hiring.
机译:细胞和分子生物学方面的发现,基因表达谱分析等新工具以及来自人类基因组序列的信息正在汇聚在一起,以拓宽工业癌症研究的就业前景。事实证明,使用这些来源进行“合理”设计的首批抗癌药物中的两种-赫赛汀(一种基于蛋白质的乳腺癌治疗方法)和格列卫(一种用于某些形式的白血病的小分子化学疗法)-已证明是成功的,而其他药物如阿瓦斯汀和Erbitux已步其后尘。这种趋势在癌症研发方面创造了一些亮点,尽管总体而言,药物发现受到合并,一些引人注目的失败以及美国经济不稳定的不利影响。马萨诸塞州沃尔瑟姆市阿斯利康研发中心的癌症研究副总裁杰夫·汉克说:“每个人都意识到,所有新信息将带来很多机会。”他说,强劲的医疗需求和大量的新科学使这段时间成为了一个巨大的推动力。考虑到这一点,该公司在过去几年中聘请了美国和英国的研发人员,并在沃尔瑟姆建立了新的癌症治疗机构。尽管机会是零散的,但有些公司正在扩大癌症研究领域,而有些则没有,但目前招聘人数普遍上升。

著录项

  • 来源
    《Nature》 |2004年第6980期|p.348-349|共2页
  • 作者

    Ricki Lewis;

  • 作者单位

    Scotia, New York;

  • 收录信息 美国《科学引文索引》(SCI);美国《工程索引》(EI);美国《生物学医学文摘》(MEDLINE);美国《化学文摘》(CA);
  • 原文格式 PDF
  • 正文语种 eng
  • 中图分类 自然科学总论;
  • 关键词

  • 入库时间 2022-08-18 02:57:01

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