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A photonic nano-Bragg grating device integrated with microfluidic channels for bio-sensing applications

机译:集成了微流通道的光子纳米布拉格光栅装置,用于生物传感应用

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摘要

A photonic wire Bragg grating structure, integrated with fluidic channels and reservoirs for fluid sensing based on refractive index changes, has been designed using 3-D Finite Domain Time Difference (FDTD) method and fabricated using electron beam lithography and reactive ion etching on an Silicon-on-lnsu-lator (SOI) material. A scheme is developed where a Polydimethylsiloxane (PDMS) microfluidic chip is integrated with the SOI photonic chip via a reversible active sealing method. The highest sensitivity (An/AA.) of the device is estimated to be 5.5 × 10~(-3)nm~(-1) and the volume of the sensing region is approximately 2 μm~3. This device could be a potential candidate for lab-on-a-chip devices for bio-sensing applications.
机译:使用3-D有限域时差(FDTD)方法设计了集成了流体通道和储层的光子线布拉格光栅结构,该流体通道和储层用于基于折射率变化的流体感测,并通过电子束光刻和反应离子刻蚀在硅上制造绝缘体上(SOI)材料。开发了一种方案,其中通过可逆主动密封方法将聚二甲基硅氧烷(PDMS)微流体芯片与SOI光子芯片集成在一起。器件的最高灵敏度(An / AA。)估计为5.5×10〜(-3)nm〜(-1),感应区域的体积约为2μm〜3。该设备可能是用于生物传感应用的芯片实验室设备的潜在候选者。

著录项

  • 来源
    《Microelectronic Engineering》 |2009年第6期|1488-1490|共3页
  • 作者单位

    Emerging Communications Technology Institute, Faculty of Applied Science and Engineering, University of Toronto, 10 King's College Road, Toronto, Ontario, Canada M5S 3C4;

    Emerging Communications Technology Institute, Faculty of Applied Science and Engineering, University of Toronto, 10 King's College Road, Toronto, Ontario, Canada M5S 3C4;

    Emerging Communications Technology Institute, Faculty of Applied Science and Engineering, University of Toronto, 10 King's College Road, Toronto, Ontario, Canada M5S 3C4;

    Optoelectronics Research Croup, Department of Electronics and Electrical Engineering, University of Glasgow, Oakfield Avenue, Clasgow, C12 8LT, Scotland, UK;

    Optoelectronics Research Croup, Department of Electronics and Electrical Engineering, University of Glasgow, Oakfield Avenue, Clasgow, C12 8LT, Scotland, UK Dipartimento di Elettronica Informatica e Sistemistica, University of Bologna, Viale Risorgimento 2, 140136 Bologna, Italy;

  • 收录信息 美国《科学引文索引》(SCI);美国《工程索引》(EI);美国《生物学医学文摘》(MEDLINE);
  • 原文格式 PDF
  • 正文语种 eng
  • 中图分类
  • 关键词

    bragg grating; photonic band-gap; nano-biosensor; lab-on-a-chip; microfluidic; micro total analysis systems; optofluidic systems;

    机译:布拉格光栅光子带隙纳米生物传感器芯片实验室微流体微观总体分析系统;光流体系统;

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