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Novel bioactive nanohydroxyapatite/polyamide66 composite membrane for guided bone regeneration

机译:新型生物活性纳米羟基磷灰石/聚酰胺66复合膜用于引导性骨再生

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摘要

To overcome the drawbacks of guided bone regeneration membranes used currently and to provide an optimal alternative, a nanohydroxyapatite/polyamide66 composite with high bioactivity was employed to develop a novel asymmetric structure porous membrane. The membrane showed a gradient porous structure. The SEM analysis revealed that pores <10 μm and pores with the size range approximately from 30 to 200 μm distributed in the relative dense layer and the spongy structure layer respectively. In vivo studies suggest that the membrane has good biocompatibility. The fibrous tissue was observed to grow into the spongy structure layer of the membrane, but the ingrowth was prevented by the relative dense layer. The membrane can meet the requirement of guided bone regeneration techniques.
机译:为了克服目前使用的引导骨再生膜的缺点并提供最佳替代方案,采用具有高生物活性的纳米羟基磷灰石/聚酰胺66复合材料开发了一种新型的不对称结构多孔膜。该膜显示出梯度多孔结构。 SEM分析表明,<10μm的孔和尺寸范围约为30-200μm的孔分别分布在相对致密层和海绵状结构层中。体内研究表明该膜具有良好的生物相容性。观察到纤维组织生长到膜的海绵结构层中,但是通过相对致密的层防止了向内生长。该膜可以满足引导骨再生技术的要求。

著录项

  • 来源
    《Materials Research Innovations》 |2008年第2期|p.98-101|共4页
  • 作者单位

    J. D. Li1,2, Y. Zuo1, X. M. Cheng1,2, C. Huang3 and Y. B. Li*1;

    1Research Center for Nanobiomaterials, Analytical and Testing Center,Sichuan University, Chengdu 610064, China2College of Chemistry, Sichuan University, Chengdu 610064, China3College of Stomatology, Sichuan University, Chengdu 610041, China;

  • 收录信息 美国《科学引文索引》(SCI);美国《工程索引》(EI);美国《生物学医学文摘》(MEDLINE);
  • 原文格式 PDF
  • 正文语种 eng
  • 中图分类
  • 关键词

    HYDROXYAPATITE/POLYAMIDE66; ASYMMETRIC MEMBRANE; COMPOSITE MATERIALS; GUIDED BONE REGENERATION;

    机译:羟基磷灰石/聚酰胺66;不对称膜复合材料;引导骨再生;
  • 入库时间 2022-08-17 23:43:45

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