Plasma Levels of Vitellogenin and Eggshell Zon Radiata Proteins in 4-Nonylphenol and o, p'-DDT Treated Juvenile Atlantic Salmon (Salmo salar)

摘要

Induction of vitellogenin (Vtg) in males and juveniles of oviparous vertebrates has been used as a biomarker for xenoestrogens. Recently, we have demonstrated that synthesis of eggshell zona radiata proteins (Zrp) or zonagenesis is an inte- gral aspect of fish oogenesis (Oppen-Berntsen et al. (1994) Journal of Experi- mental Zoology 268, 59-70), and that Zrp synthesis is a sensitive biomarker for nonylphenol (Arukwe et al. (1997) Environmental Health Perspective 105, 418-422). This study compares the responses of Vtg and Zrp in plasma of juve- nile Atlantic salmon (Salmo salar) treated with 4-nonylphenol (NP) and o, p'- DDT (both at 25 mg kg~-1, singly and in combination).