Involvement and loss of function of nerves, cutaneous as well as trunk nerves, is the main cause of impairment. The subsequent disability leads to a handicap in leprosy. Early intervention at the stage of impairment is the best way to prevent deformity, disability, the stigma and fear of leprosy. The next best is intervention at the stage of early deformity and disability before it becomes established and irreversible. A positive attitude an motivation on the part of the patient, doctor and all involved in this work, is essential.
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