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Increased levels of nitric oxide metabolites in urine from leprosy patients in reversal reaction

机译:麻风病人尿液中一氧化氮代谢物水平升高

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We measured the metabolites of NO[nitrite(NO~-_2)and nitrate(NO~-_3)]in urine form Ehiopian patients suffering from leprosy. The urinary level of NO~-_2/NO~-_3 in a group of healthy Ehiopians was 1020±471μM(n = 22). Leprosy patients in reversal reaction had significantly higher levels of NO~-_2/NO~-_3(1817±492μM, p < 0.001, n = 12)than both the control group and leprosy patients who were not in reversal reaction(1079±446μM, n = 12). We concluded that the reversal reaction in leprosy is associated with increased urinary levels of nitric oxide metabolites.
机译:我们测量了患有麻风的埃塞俄比亚患者尿液中NO [亚硝酸盐(NO〜-_2)和硝酸盐(NO〜-__ 3)]的代谢产物。一组健康的埃塞俄比亚人尿中NO〜-_2 / NO〜-__ 3水平为1020±471μM(n = 22)。麻风患者逆转反应的NO〜-_2 / NO〜-_3水平显着高于对照组和未逆转麻风病患者(1079±446μM)(1817±492μM,p <0.001,n = 12) ,n = 12)。我们得出的结论是,麻风病的逆转反应与一氧化氮代谢产物的尿水平升高有关。

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