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Behavioral interference and C/EBPβ expression in the insular-cortex reveal a prolonged time period for taste memory consolidation

机译:岛皮层中的行为干扰和C /EBPβ表达表明味觉记忆巩固的时间延长

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Memory consolidation is defined as the time window during which the memory trace is susceptible to behavioral, electrical, or pharmacological interventions. Here, we presented rats with two novel tastes at consecutive time intervals. Clear interference was evident when a novel taste formed the second taste input whereby, surprisingly, the time window for interference was found to last more than 10 h. In addition, we detected an increase of C/EBPβ protein expression in the gustatory cortex 18 h after novel taste learning. This modulation was attenuated by a subsequent novel taste. Our findings reveal temporal constraints and a lingering nature of taste memory consolidation.
机译:记忆合并定义为记忆跟踪易受行为,电或药理学干预的时间窗口。在这里,我们以连续的时间间隔向大鼠展示了两种新口味。当新的口味形成第二种口味输入时,明显的干扰是显而易见的,令人惊讶的是,发现干扰的时间窗口持续了超过10小时。此外,我们发现新的味觉学习后18 h,味觉皮质中C /EBPβ蛋白表达增加。随后的新颖味道减弱了这种调节。我们的发现揭示了时间限制和味觉记忆巩固的持久特性。

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