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A Web-accessible distributed data warehouse forbrain tumour diagnosis

机译:可通过Web访问的分布式数据仓库,用于脑肿瘤诊断

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摘要

Currently, biological databases (DBs) are a common tool to complement the research of a wide range of biomedical disciplines, but there are only a few specialized medical DBs for human brain tumour magnetic resonance spectroscopy (MRS) data; they typically store a limited range of biological data (i.e. clinical information, magnetic resonance imaging and MRS data) and are not offered as open-source Structured Query Language relational DB schemas. We present a novel approach to biological DBs: a distributed Web-accessible DB for storing and managing clinical and biomedical data related to brain tumours from different clinical centres. This tool is designed for multi-platform systems with dissimilar DB management systems. Being the main data repository of the HealthAgents (HA) project, it uses multi-agent technology and allows the centres to share data and obtain diagnosis classifications from other centres distributed around the world in a reliable way. The HA project aims to create an agent-based distributed decision support system (DSS) to assist doctors to provide a brain tumour diagnosis and prognosis. The HA DB enables the DSS to totally integrate with its Graphical User Interface to perform classifications with the stored data and visualize the results using the HA distributed agents framework. This new feature converts the system presented in the first application in the world to combine a storage and management tool for brain tumour data and a complete Web-based DSS to obtain automatic diagnosis.
机译:当前,生物数据库(DBs)是补充广泛的生物医学学科研究的通用工具,但是只有少数几个专门的医学数据库可用于人脑肿瘤磁共振波谱(MRS)数据。它们通常存储有限范围的生物学数据(即临床信息,磁共振成像和MRS数据),并且不作为开源结构化查询语言关系数据库模式提供。我们为生物数据库提供了一种新颖的方法:分布式Web可访问的数据库,用于存储和管理与来自不同临床中心的脑瘤相关的临床和生物医学数据。该工具设计用于具有不同DB管理系统的多平台系统。作为HealthAgents(HA)项目的主要数据存储库,它使用多代理技术,并允许各中心以可靠的方式共享数据并从分布在世界各地的其他中心获取诊断分类。 HA项目旨在创建一个基于代理的分布式决策支持系统(DSS),以帮助医生提供脑肿瘤的诊断和预后。 HA DB使DSS能够与其图形用户界面完全集成,从而使用HA分布式代理框架对存储的数据进行分类并可视化结果。这项新功能转换了世界上第一个应用程序中提出的系统,将脑肿瘤数据的存储和管理工具与完整的基于Web的DSS相结合,以获得自动诊断。

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  • 来源
    《The Knowledge Engineering Review》 |2011年第3期|p.329-351|共23页
  • 作者单位

    MicroArt, Pare Cientific de Barcelona, Baldiri Reixac 4-6, 08028, Barcelona, Catalonia, Spain;

    MicroArt, Pare Cientific de Barcelona, Baldiri Reixac 4-6, 08028, Barcelona, Catalonia, Spain;

    MicroArt, Pare Cientific de Barcelona, Baldiri Reixac 4-6, 08028, Barcelona, Catalonia, Spain;

    MicroArt, Pare Cientific de Barcelona, Baldiri Reixac 4-6, 08028, Barcelona, Catalonia, Spain;

    Pharma Quality Europe, Via Brunetto degli Innocenti, 2-50063 Figline Valdarno (Fl), Italy;

    MicroArt, Pare Cientific de Barcelona, Baldiri Reixac 4-6, 08028, Barcelona, Catalonia, Spain;

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  • 正文语种 eng
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  • 入库时间 2022-08-18 00:38:49

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