Basic Properties of Apatite Cement Containing Carbonate Apatite and Its Resorption by Cultured Osteoclasts

摘要

Apatite cement (AC) has received much attention as a new reconstructive material for bony defects because AC transforms to hydroxyapatite (HAP) and shows excellent tissue response and osteoconductivity. In addition, AC has been reported to be partly replaced with bone, although the process takes a long time. The aim of this study, therefore, is to fabricate bone-replacing apatite cement by converting AC to be easily resorbed by osteoclasts. For this purpose, NaHCO_3 was added into the AC component.