THE INFLUENCE OF POLYELECTROLYTES ON THE FORMATION AND PHASE TRANSFORMATION OF AMORPHOUS CALCIUM PHOSPHATE

摘要

The formation of amorphous calcium phosphate (ACP) and its transformation into octacalcium phosphate (OCP) in the presence of poly-l-glutamic acid (PGA, Mw 3 000 D and 50 000 D), poly-l-lysine (PLL, Mw 50 000 D) and polystyrene sulfonate (PSS, MW 70 000 D) has been investigated. All polyelectrolytes at low concentrations induced and at high concentrations retarded nucleation of the crystalline precipitate. In addition, the polyelectrolytes inhibited aggregation of ACP particles and growth of the crystalline phase. The intensity of the effects depended on the charge, molecular mass, and concentration of the specific polymer.