Effect of Bioactive Glass/Cement Weight Ratio on Bioactivity and Biocompatibility of a Bioactive Glass Modified Glass Ionomer Cement

摘要

The bioactivity of a glass ionomer luting cement (Ketac~®-cem, ESPE, Germany), which was modified by Bioglass~® (PerioGlas~® Synthetic Bone Graft Particulate, US Biomaterials) in different bioglass/powder weight ratios, and the biocompatibility of the produced mixtures were evaluated in this study using different cell lines. The incorporation of Bioglass~® in the cement structure resulted in the formation of sparsely located biological apatite aggregations. However, although Bioglass~® incorporation seemed to enhance cell proliferation, the materials became eventually brittle and highly soluble depending on Bioglass~® amount.