Correlations between Chemical Compositions and Retention Times of Methacrylate Random Copolymers Using LC-ESI-MS

摘要

Correlations between chemical compositions and chromatographic retention times (Rt) of methacrylate random copo-lymers were studied by liquid chromatography electrospray ionization mass spectrometry (LC-ESI-MS). Twenty-six differ-ent polymers including homopolymers of polylmethyl methacrylate) (PMMA), poly(tert-butyl methacrylate) (PTBMA) and poly(2-hydroxyefhyl methacrylate) (PHEMA), and their random copolymers of P(MMA-TBMA) and P(MMA-HEMA) with known chemical compositions were studied. The results indicate that there is close correlations between the chemical compo-sitions of the random copolymers and their Rt of the C8 column in the mass spectral ranges of m/z 1,800-2,000. The LC-ESI-MS analysis showed molecular weights of the copolymers distribute in the mass range of ca. 500-20,000, and the structures of polymer terminals and their monomer units can be identified.