TERPENE SYNTHASE COTB2: AN ENERGETIC BALANCING ACT

摘要

Terpene synthases are a family of enzymes that catalyze the biosynthesis of terpenes, a class of hydrocarbon molecules with important pharmaceutical and commercial applications. Terpene synthases employ a vast array of precisely controlled carbocation reactions to generate various terpene products. Historically, understanding how the terpene synthase active site drives this complex carbocation chemistry has been limited by the lack of biologically relevant enzyme crystal structures available.