Enantioselective Friedel-Crafts Alkylations of α,β-Unsaturated 2-Acyl Imidazoles Catalyzed by Bis(oxazolinyl)pyridine-Scandium(III) Triflate Complexes

摘要

α,β-unsaturated 2-acyl imidazoles are efficient substrates for Friedel—Crafts alkylations. These substrates are easily converted to a variety of useful functional groups and are easily synthesized. Further studies to explain the catalyst loading profile and expand the scope of the reactions of the α,β-unsaturated 2-acyl imidazoles are in progress.