Highly Regioselective Ir-Catalyzed β-Borylation of Porphyrins via C-H Bond Activation and Construction of β-β-Linked Diporphyrin

摘要

We have achieved highly regioselective borylation of meso-arylporphyrins via C—H bond activation under iridium catalysis. This protocol offers an effective method for β-function-alization of porphyrins, which is otherwise inaccessible or entails multistep synthesis. One key feature is that the reaction does not hurt the usually reactive meso-positions. Functionalization of β-borylated porphyrins by taking advantage of rich organoboron chemistry and exploitation of them for fabrication of multiporphy-rinic compounds are currently underway in our laboratory.