Efficient Preparation of Functionalized Hybrid Organic/ Inorganic Wells-Dawson-type Polyoxotungstates

摘要

Hybrid organic/inorganic Wells-Dawson polyoxotungstates have been prepared through addition of functionalized tricholorostannanes to lacunary α_2- and α_1-[P_2W_(17)O_(61)]~(10-). Coupling of amines and alcohols to polyoxotungstate platforms led to new structures in good yields. Coupling of chiral amines to the previously unknown organotin-substituted α_1 derivatives allowed the isolation of diastereomers, which feature in some cases split ~1H, ~(13)C, and ~(31)P NMR spectra. This is the first example of NMR observation of a single pair of diastereomers in the α_1 -Wells-Dawson series. It opens the way to potential resolution of those chiral polyoxotungstates.