Charge-Transfer Transitions in Protein Circular Dichroism Calculations

摘要

The UV absorption spectra of proteins contain many features that can be exploited in studies of protein folding.The far UV spectrum is dominated by an intense band at 190 nm,due to the electronically allowed pi_(nb)-> pi* transitions in the backbone peptide units.A very weak signal at 222 nm arises from the electrically forbidden n -> pi* transitions.At even higher energy,the vacuum ultraviolet(VUV)region also contains strong absorptions,but their origin is not well established,and charge-transfer transitions are a possible source.