Phosphorus Ligands in Asymmetric Catalysis: Synthesis and Applications, Volumes 1 -3

摘要

Chiral bivalent phosphorus compounds are important ligands in metal-catalyzed asymmetric syntheses. According to Borner's introduction, tens of thousands of these ligands have been prepared and tested, while, in a later chapter, Thommen and Blaser quote typical large-scale prices for commercial ligands of $5000 to more than $40,000 per kg. Although a 1991 review on the subject required only 51 pages (see Kagan, H. B.; Sasaki, M. Optically Active Phosphines: Preparation, Uses and Chi-roptical Properties. In The Chemistry of Organophosphorus Compounds; Hartley, F. R., Ed.; John Wiley and Sons, Ltd.: Chichester, 1990; Vol. 1, pp 51-102), the huge size of this three-volume set reveals recent interest in this class of compounds. It could have been even longer: for example, in Shang and Zhang's 42-page chapter on chiral phosphacycles, they note that a word limit precluded complete coverage, and the 47-page review on P/NR_2 ligands by McManus et al. is also described as not comprehensive. However, some duplication is avoided by the citation of other reviews, and the three volumes present both broad coverage and considerable detail.