Iron-Catalyzed Aminohydroxylation of Olefins

摘要

The osmium-catalyzed Sharpless aminohydroxylation is a powerful method for the rapid transformation of alkenes into 1,2-aminoalcohols. Because of the cost and toxicity of osmium salts, however, a variety of alternate methods for olefin oxyamination that utilize palladium and copper catalysts have been developed.