Nickel-Catalyzed Cycloaddition of o-Arylcarboxybenzonitriles and Alkynes via Cleavage of Two Carbon-Carbon a Bonds

摘要

An intermolecular cycloaddition reaction has been developed, where o-aryicarboxybenzonitriles react with alkynes to afford coumarins in the presence of Ni(0)/P(CH2Ph)3/MAD as a catalyst. The reaction process displays an unusual mechanistic feature-the cleavage of two independent C-CN and C-CO bonds.