首页> 外文期刊>Journal of the American Chemical Society >Zinc-Ligand Swapping Mediated Complex Formation and Sulfur Transfer between SufS and SufU for Iron-Sulfur Cluster Biogenesis in Bacillus subtilis
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Zinc-Ligand Swapping Mediated Complex Formation and Sulfur Transfer between SufS and SufU for Iron-Sulfur Cluster Biogenesis in Bacillus subtilis

机译:锌-配体交换介导的复合物形成和SufS和SufU之间的硫转移,用于枯草芽孢杆菌中铁硫簇的生物发生。

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摘要

SufU is a zinc-containing protein involved in mobilization of sulfur from SufS for iron–sulfur cluster biogenesis of Bacillus subtilis . Structural basis for the sulfur transfer in SufS–SufU complex was revealed. A zinc-ligand exchange reaction upon SufS–SufU complexation provides a free thiol from Cys41 of SufU as a sulfur acceptor.
机译:SufU是一种含锌蛋白,参与从SufS转移硫来实现枯草芽孢杆菌的铁硫簇生物发生。揭示了SufS–SufU复合物中硫转移的结构基础。 SufS–SufU络合后的锌-配体交换反应提供了SufU的Cys41中的游离硫醇作为硫受体。

著录项

  • 来源
    《Journal of the American Chemical Society》 |2017年第51期|18464-18467|共4页
  • 作者单位

    Department of Biochemistry and Molecular Biology, Graduate School of Science and Engineering, Saitama University, Shimo-ohkubo 255, Sakura-ku, Saitama 338-8570, Japan;

    Department of Biochemistry and Molecular Biology, Graduate School of Science and Engineering, Saitama University, Shimo-ohkubo 255, Sakura-ku, Saitama 338-8570, Japan;

    Department of Biochemistry and Molecular Biology, Graduate School of Science and Engineering, Saitama University, Shimo-ohkubo 255, Sakura-ku, Saitama 338-8570, Japan;

    Department of Biochemistry and Molecular Biology, Graduate School of Science and Engineering, Saitama University, Shimo-ohkubo 255, Sakura-ku, Saitama 338-8570, Japan;

    Department of Biochemistry and Molecular Biology, Graduate School of Science and Engineering, Saitama University, Shimo-ohkubo 255, Sakura-ku, Saitama 338-8570, Japan;

    Department of Bioscience, Graduate School of Agriculture, Tokyo University of Agriculture, Sakuragaoka 1-1-1, Setagaya-ku, Tokyo 156-8502, Japan;

    Department of Biochemistry and Molecular Biology, Graduate School of Science and Engineering, Saitama University, Shimo-ohkubo 255, Sakura-ku, Saitama 338-8570, Japan;

  • 收录信息 美国《科学引文索引》(SCI);美国《工程索引》(EI);美国《生物学医学文摘》(MEDLINE);美国《化学文摘》(CA);
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  • 正文语种 eng
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  • 入库时间 2022-08-18 03:08:11

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