Oxidatively Induced C-H Activation at High Valent Nickel

摘要

This communication describes a series of oxidatively induced intramolecular arene C-H activation reactions of Ni~(II) model complexes to yield Ni~(IV) σ-aryl products. These reactions proceed within 10 min at room temperature, which represents among the mildest conditions reported for C-H cleavage at a Ni center. A combination of density functional theory and preliminary experimental mechanistic studies implicate a pathway involving initial 2e~ oxidation of the Ni~(II) starting materials by the F~+ transfer reagent N-fluoro-2,4,6-trimethylpyr-idinium triflate followed by triflate-assisted C-H cleavage at Ni~(IV) to yield the products.