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Group Testing with Random Pools: Phase Transitions and Optimal Strategy

机译:带有随机池的组测试:相变和最佳策略

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The problem of Group Testing is to identify defective items out of a set of objects by means of pool queries of the form “Does the pool contain at least a defective?”. The aim is of course to perform detection with the fewest possible queries, a problem which has relevant practical applications in different fields including molecular biology and computer science. Here we study GT in the probabilistic setting focusing on the regime of small defective probability and large number of objects, p→0 and N→∞. We construct and analyze one-stage algorithms for which we establish the occurrence of a non-detection/detection phase transition resulting in a sharp threshold, [`(M)]overline{M} , for the number of tests. By optimizing the pool design we construct algorithms whose detection threshold follows the optimal scaling [`(M)] µ Np|logp|overline{M}propto Np|log p| . Then we consider two-stages algorithms and analyze their performance for different choices of the first stage pools. In particular, via a proper random choice of the pools, we construct algorithms which attain the optimal value (previously determined in (Mézard and Toninelli, arXiv:0706.3104)) for the mean number of tests required for complete detection. We finally discuss the optimal pool design in the case of finite p.
机译:组测试的问题是,通过“以下格式的池查询是否至少包含一个缺陷?”来从一组对象中识别出缺陷项目。目的当然是用最少的查询来执行检测,这个问题在分子生物学和计算机科学等不同领域具有相关的实际应用。在这里,我们在概率环境下研究GT,着眼于次品率低且对象数量大的状态,p→0和N→∞。我们构建并分析了一个阶段算法,针对该算法,我们建立了非检测/检测相变的发生,从而导致测试次数急剧增加,阈值[`(M)] overline {M}。通过优化池设计,我们构建了算法,其检测阈值遵循最佳比例[`(M)] µ Np | logp | overline {M} propto Np | log p | 。然后,我们考虑两阶段算法,并分析其对于第一阶段池的不同选择的性能。尤其是,通过适当地随机选择池,我们可以构建算法,以达到完整检测所需平均测试次数的最佳值(先前在(Mézard和Toninelli,arXiv:0706.3104中确定)。最后,我们讨论了在有限p情况下的最佳池设计。

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