Scientific facts behind creatine monohydrate as sport nutrition supplement

摘要

Currently, strong efforts are being made toward demonstrating pos- sible risks of using pure creatine monohydrate (Cr.H_2O). In this article, scientific facts and considerations are presnted, which support such concern. A further attempt is made to pursue the concept of possible risks of uncontrolled supplementation in ath- letes with pure Cr.H_2O. The problem is viewed form the scientif- ic evidence that a highly conservative mechanism of homeostatic feed-back inhibitory self-regulation of Cr biosynthesis in the body has been evolutionary developed.