Novel 7- and 8-Endo 2-Indolylacyl Radical Cyclizations: Efficient Construction of Azepino- and Azocinoindoles

摘要

Regioselective 7- and 8-endo cyclizations of selenoester derived 2-indolylacyl radicals upon amino tethered alkenes have been used to synthesize azepino[3,2-b]- and azocino-[4,3-b]indoles, which are tricyclic subunits present in the indole alkaloids mersicarpine and apparicine, respectively.