1-Benzotriazol-1-yl-3,3,3-trifluoro-2-methoxy-2-phenylpropan-1-ones: Mosher-Bt Reagents

Alan R. Katritzky; Prabhu P. Mohapatra; Dmytro Fedoseyenko; Matthew Duncton; Peter J. Steel

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1-Benzotriazol-1-yl-3,3,3-trifluoro-2-methoxy-2-phenylpropan-1-ones: Mosher-Bt Reagents

机译：1-Benzotriazol-1-yl-3,3,3-trifluoro-2-methoxymethoxy-2-phenylpropan-1-ones：Mosher-Bt试剂

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摘要

Benzotriazole derivatives of 3,3,3-trifluoro-2-methoxy-2-phenylpropionic acid react with water-soluble amino acids and peptides in an acetonitrile/water (2:1) mixture to give the corresponding amides in quantitative yield.

机译：3,3,3-三氟-2-甲氧基-2-苯基丙酸的苯并三唑衍生物与水溶性氨基酸和肽在乙腈/水（2：1）混合物中反应，以定量收率得到相应的酰胺。

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来源
《The Journal of Organic Chemistry》 |2007年第11期|p.4268-4271|共4页
作者
Alan R. Katritzky; Prabhu P. Mohapatra; Dmytro Fedoseyenko; Matthew Duncton; Peter J. Steel;
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作者单位

Center for Heterocyclic Compounds, Department of Chemistry, University of Florida, Gainesville, Florida 32611-7200;

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收录信息美国《科学引文索引》(SCI);美国《工程索引》(EI);美国《生物学医学文摘》(MEDLINE);美国《化学文摘》(CA);
原文格式 PDF
正文语种 eng
中图分类有机化学;
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入库时间 2022-08-18 00:02:17

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1. 1-benzotriazol-1-yl-3,3,3-trifluoro-2-methoxy-2-phenylpropan-1-ones: Mosher-bt reagents [J] . Katritzky AR, Mohapatra PP, Fedoseyenko D, The Journal of Organic Chemistry . 2007,第11期

机译：1-苯并三唑-1-基-3,3,3-三氟-2-甲氧基-2-苯基丙烷-1-酮：Mosher-bt试剂
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机译：用于生物分子的Astatination试剂。 6.通过巯基基团与马来酰亚胺基-c / oso-Decaborate（2-）试剂结合的完整抗体的肾脏浓度明显高于通过赖氨酸胺与异硫氰酸基-c / oso-Decaborate（2-）试剂结合的相同抗体。
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6. Reagents for astatination of biomolecules. 6. An intact antibody conjugated with a maleimido-closo-decaborate(2-) reagent via sulfhydryl groups had considerably higher kidney concentrations than the same antibody conjugated with an isothiocyanato-closo-decaborate(2-) reagent via lysine amines [O] . D. Scott Wilbur, Ming-Kuan Chyan, Hirohisa Nakamae, -1

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7. 1-Benzotriazol-1-yl-3,3,3-trifluoro-2-methoxy-2-phenylpropan-1-ones: Mosher-Bt Reagents. [O] . Alan R. Katritzky, Prabhu P. Mohapatra, Dmytro Fedoseyenko, 2007

机译：1-苯并噻唑-1-基-3,3,3-三氟氟-2-甲氧基-2-苯基丙烷-1-甲氧 - BT试剂。

1-Benzotriazol-1-yl-3,3,3-trifluoro-2-methoxy-2-phenylpropan-1-ones: Mosher-Bt Reagents

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