Aggregate Cardiovascular Risk Is a Stronger Statistical Correlate of Clinically Evident Diabetic Peripheral Neuropathy Than HbA^sub 1c^ Alone

摘要

Apart from chronic hyperglycemia measured by hemoglobin A1c (HbA1c), other vascular risk factors contribute to the development of diabetic neuropathy. Even though these factors are synergistic, no study has measured the relative effect of aggregate cardiovascular risk load compared with chronic hyperglycemia alone on the risk of clinically evident diabetic peripheral neuropathy.