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Acceleration of amphibian forelimb regeneration by polypeptide growth factors

机译:多肽生长因子促进两栖动物前肢再生

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摘要

Growth factors are potentially important modulators of epimorphic regeneration. This study examined effects of intraperitoneal administration of selected growth factors on limb regeneration of adult nests, Notophthalmus viridescens. These agents stimulated regeneration, producing overlapping but nonidentical effect. Fibroblast growth factor-2 (FGF-2) and insulin-like growth factor I (IGF-I) stimulated bud emergence (8.3 ± 0.6 and 8.3 ± 0.7 days, respectively, vs 11.4 ± 1.1 days for controls).
机译:生长因子是表观再生的潜在重要调节剂。这项研究检查了腹膜内施用某些生长因子对成年巢线虫(Notophthalmus viridescens)肢体再生的影响。这些物质刺激再生,产生重叠但不同的作用。成纤维细胞生长因子2(FGF-2)和胰岛素样生长因子I(IGF-1)刺激芽萌发(分别为8.3±0.6和8.3±0.7天,而对照组为11.4±1.1天)。

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