Wound Repair

摘要

Following injury, a series of events is initiated that includes global and local reactions. Global reactions, such as inflammatory and immunological responses as well as adjustments in neural and endocrine status, are directed at marshaling the organism's resources for dealing with changes in its integrity and the potential threat of infection or other complications. Injury entails cell and tissue damage and often a physical breach in the barrier against the outside world (e. g., skin). Local reactions are exemplified by immediate hemostatic (e. g., blood clotting) events followed by changes in local cellular composition created by the inflammatory infiltrate and adjustments in resident cell function.